Title Effect of Inquiry-Based Stress Reduction on Well-being and Views on Risk-Reducing Surgery Among Women With BRCA Variants in Israel
Question Does the inquiry-based stress reduction technique improve the psychological well-being, sleep quality, and psychosocial variables and change views on risk-reducing surgery in women in Israel with BRCA1/BRCA2 variants?
Findings This randomized clinical trial including 100 patients using an IBSR intervention found that IBSR improved the well-being and sleep quality of women with BRCA1/BRCA2 variants. After the intervention, the participants who underwent IBSR had more favorable view on risk-reducing oophorectomy and mastectomy.
Meaning These findings suggest that IBSR may be used as a tool to enhance the psychological well-being of women with BRCA variants and support them in considering risk-reducing surgery.